Discovery and preclinical profile of LX-039, a novel indole-based oral selective estrogen receptor degrader (SERD)

作者：Jianyu Lu, Chi-Chung Chan, Deheng Sun, Guoping Hu, Huijun He, Jian Li, Jiaqiang Dong, Kai Liu, Liang Shen, Lihong Hu, Qingyang Gu, Shuhui Chen, Tielin Wang, Ting Gong, Wei Tang, Xiaoting Li, Xiaotong Zhu, Xu Zeng, Ying‐Jie Zhu, Yuanfeng Xia, Yuanyuan Huang, Yusong Zhu, Zhenteng Liu, Charles Z. Ding · 发表于：Bioorganic & Medicinal Chemistry Letters · 年份：2022 · DOI：10.1016/j.bmcl.2022.128734 · 被引用次数：16 · 研究领域：Estrogen and related hormone effects、HER2/EGFR in Cancer Research、Click Chemistry and Applications