Discovery and structural optimization of potent epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M/C797S resistance mutation for lung cancer treatment

作者：Cheng Wang, Xin Wang, Zhi Huang, Tianqi Wang, Yongwei Nie, Shengyong Yang, Rong Xiang, Yan Fan · 发表于：European Journal of Medicinal Chemistry · 年份：2022 · DOI：10.1016/j.ejmech.2022.114381 · 被引用次数：14 · 研究领域：Lung Cancer Treatments and Mutations、HER2/EGFR in Cancer Research、Cancer therapeutics and mechanisms