Who Is at Risk of Poor Mental Health Following Coronavirus Disease-19 Outpatient Management?

作者：Katharina Hüfner, Piotr Tymoszuk, Dietmar Ausserhofer, Sabina Sahanic, Alex Pizzini, Verena Rass, Mátyás Gálffy, Anna Böhm, Katharina Kurz, Thomas Sonnweber, Ivan Tancevski, Stefan Julia Kiechl, Andreas Huber, Barbara Plagg, Christian Josef Wiedermann, Rosa Bellmann‐Weiler, Herbert Bachler, Günter Weiß, Giuliano Piccoliori, Raimund Helbok, Judith Löffler‐Ragg, Barbara Sperner‐Unterweger · 发表于：Frontiers in Medicine · 年份：2022 · DOI：10.3389/fmed.2022.792881 · 被引用次数：37 · 研究领域：COVID-19 and Mental Health、Long-Term Effects of COVID-19、Pharmacological Receptor Mechanisms and Effects

Background: mental health disorder or worsening of a pre-existing one. COVID-19 outpatients have been less well characterized than their hospitalized counterparts. The objectives of our study were to identify indicators for poor mental health following COVID-19 outpatient management and to identify high-risk individuals. Methods: = 893). Primary endpoints were positive screening for depression and anxiety (Patient Health Questionnaire; PHQ-4) and self-perceived overall mental health (OMH) and quality of life (QoL) rated with 4 point Likert scales. Psychosocial stress was surveyed with a modified PHQ stress module. Associations of the mental health and QoL with socio-demographic, COVID-19 course, and recovery variables were assessed by multi-parameter Random Forest and Poisson modeling. Mental health risk subsets were defined by self-organizing maps (SOMs) and hierarchical clustering algorithms. The survey analyses are publicly available (https://im2-ibk.shinyapps.io/mental_health_dashboard/). Results: Depression and/or anxiety before infection was reported by 4.6% (IT)/6% (AT) of participants. At a median of 79 days (AT)/96 days (IT) post-COVID-19 onset, 12.4% (AT)/19.3% (IT) of subjects were screened positive for anxiety and 17.3% (AT)/23.2% (IT) for depression. Over one-fifth of the respondents rated their OMH (AT: 21.8%, IT: 24.1%) or QoL (AT: 20.3%, IT: 25.9%) as fair or poor. Psychosocial stress, physical performance loss, high numbers of acute and sub-acute COVID-19 com...