A case of generalized morphea profunda following SARS-CoV-2 infection

作者：Michael Stephens, Duncan F. Moore, Jonathan Dau, Soma Jobbagy, Victor Neel, Marcy B. Bolster, Flavia Fedeles · 发表于：JAAD Case Reports · 年份：2022 · DOI：10.1016/j.jdcr.2022.02.033 · 被引用次数：7 · 研究领域：Systemic Sclerosis and Related Diseases、Inflammatory Myopathies and Dermatomyositis、Skin Diseases and Diabetes

Morphea is an immune-mediated fibrosing skin disorder of the dermis and subcutaneous fat with unclear pathogenesis and triggers. Combinations of genetic and environmental factors leading to immune dysregulation are likely involved. Here, we describe a case of generalized morphea profunda occurring after SARS-CoV-2 infection, and we discuss possible causality and pathogenesis.