Research Advances on Matrine

作者：Xiaoying Sun, Li-Yi Jia, Zheng Rong, Xin‐Fu Zhou, Lu-Qi Cao, Aihong Li, Meng Guo, Jie Jin, Yin-Di Wang, Ling Huang, Yi‐Heng Li, Zhong-Jing He, Long Li, Rui-Kang Ma, Yi-Fan Lv, Ke-Ke Shao, Juan Zhang, Hui‐Ling Cao · 发表于：Frontiers in Chemistry · 年份：2022 · DOI：10.3389/fchem.2022.867318 · 被引用次数：94 · 研究领域：Bioactive natural compounds、Neurological Disease Mechanisms and Treatments、Synthesis of Organic Compounds

root, etc. It has the dual advantages of traditional Chinese herbs and chemotherapy drugs. It exhibits distinct benefits in preventing and improving chronic diseases such as cardiovascular disease and tumors. The review introduced recent research progresses on extraction, synthesis and derivatization of Matrine. The summary focused on the latest research advances of Matrine on anti-atherosclerosis, anti-hypertension, anti-ischemia reperfusion injury, anti-arrhythmia, anti-diabetic cardiovascular complications, anti-tumor, anti-inflammatory, anti-bacterium, anti-virus, which would provide new core structures and new insights for new drug development in related fields.