Long-term maternal intake of inulin exacerbated the intestinal damage and inflammation of offspring rats in a DSS-induced colitis model

作者：Ying He, Xie Peng, Yang Liu, Qing Wu, Qiang Zhou, Yingyan Huang, Shiya Liu, Liang Hu, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Jian Li, Xuemei Jiang, Yong Zhuo, De Wu, Lianqiang Che · 发表于：Food & Function · 年份：2022 · DOI：10.1039/d1fo03675k · 被引用次数：21 · 研究领域：Gut microbiota and health、Child Nutrition and Feeding Issues、Infant Nutrition and Health

, which were the highest enriched in INU + DSS rats. The level of acetate in the colonic digesta of INU + DSS rats was lower than that in FFD and INU rats. These results indicated that long-term maternal intake of inulin exacerbated the intestinal damage and inflammation of DSS-induced offspring rats, associated with the decreased level of acetate and altered intestinal microbiota.