Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming

作者：Meng‐Ting Chang, Li‐Chu Tsai, Kyoko Nakagawa‐Goto, Kuo‐Hsiung Lee, Lie‐Fen Shyur · 发表于：Pharmacological Research · 年份：2022 · DOI：10.1016/j.phrs.2022.106148 · 被引用次数：43 · 研究领域：Ferroptosis and cancer prognosis、Cancer, Lipids, and Metabolism、Ubiquitin and proteasome pathways