Intracranial Metastases

作者：Peter S. Richards, Wylie McKissock · 发表于：BMJ · 年份：1963 · DOI：10.1136/bmj.1.5322.15 · 被引用次数：132 · 研究领域：Brain Metastases and Treatment、Glioma Diagnosis and Treatment、Radiopharmaceutical Chemistry and Applications

Surgical treatment is rarely considered when an intracranial metastasis is suspected, even when the primary tumour has previously been excised.We present here a study of the 389 patients with secondary intracranial tumours seen at this hospital in the years 1946-60, inclusive, in an attempt to evaluate the possibilities for useful surgical treatment and to illustrate the unpredictable behaviour of some tumours.The cases are selected in the sense that patients with intracranial metastases are usually referred here only if the primary tumour is either unsuspected or not evident, or if several years have elapsed since excision of a primary tumour and a coincidental benign intracranial tumour has to be excluded. Criteria for DiagnosisIn this series 65% of the metastases originated from bronchogenic carcinoma (Table I).There were 213 men and 39 women.The criteria used for making the diagnosis in these cases are summarized in Table II.It will be seen that in 17% no primary tumour was detect- able on the chest film taken on admission.The other sites of origin were arrived at by histological study of the metastasis, together with previous or later histological examination of the primary in all but four cases.Professor T. Crawford reported on the histology of the great majority of the metastases.TABLE I.-Analysis of 389 Intracerebral Metastases