Numerical calibration method for a multiple spectrometer-based OCT system

作者：Yusi Miao, Jun Song, Destiny Hsu, Ringo Ng, Yifan Jian, Marinko V. Šarunic, Myeong Jin Ju · 发表于：Biomedical Optics Express · 年份：2022 · DOI：10.1364/boe.450942 · 被引用次数：23 · 研究领域：Optical Coherence Tomography Applications、Retinal and Macular Surgery、Retinal Diseases and Treatments

The present paper introduces a numerical calibration method for the easy and practical implementation of multiple spectrometer-based spectral-domain optical coherence tomography (SD-OCT) systems. To address the limitations of the traditional hardware-based spectrometer alignment across more than one spectrometer, we applied a numerical spectral calibration algorithm where the pixels corresponding to the same wavelength in each unit are identified through spatial- and frequency-domain interferometric signatures of a mirror sample. The utility of dual spectrometer-based SD-OCT imaging is demonstrated through in vivo retinal imaging at two different operation modes with high-speed and dual balanced acquisitions, respectively, in which the spectral alignment is critical to achieve improved retinal image data without any artifacts caused by misalignment of the spectrometers.