Polyphenolic Fractions from Three Millet Types (Fonio, Finger millet, and Pearl millet): their Characterization and Biological Importance

作者：Oluwasesan Micheal Bello, Abiodun Busuyi Ogbesejana, Abdulrahman Balkisu, Martin Osibemhe, Bashir Musa, Stephen O. Oguntoye · 发表于：Clinical Complementary Medicine and Pharmacology · 年份：2022 · DOI：10.1016/j.ccmp.2022.100020 · 被引用次数：38 · 研究领域：Phytochemicals and Antioxidant Activities、Natural Antidiabetic Agents Studies、Food composition and properties

As antioxidant-rich plant foods, cereals can impede lipid and starch breakdown in the human body, are germane to diabetes management. We aim to identify newer sources of phytochemicals and health-promoting constituents desirable antidiabetic and antioxidant properties. Three millet types i.e. fonio (Digitaria exilis), finger millet (Eleusine coracana), and pearl millet (Pennisetum glaucum) available locally were investigated for antioxidant ability employing these assays i.e. DPPH, ABTS, H2O2, antidiabetic ability employing these assays i.e. α-amylase, α-glucosidase and inhibitory property on glycosylation formation. Preliminary characterization tools were employed i.e. UV-Visible spectroscopy (UV–visible) and Fourier-Transform Infrared Spectroscopy (FTIR) for the polyphenolic confirmation. The absorbance intensity range 325–425 nm confirmed that polyphenolics are present in the three millet types; most of the biological results showed the activities are dose-dependent. Fonio millet extract revealed the highest activity against hemoglobin glycosylation (29.469 ± 0.399%) which compared favorably with the standard (acarbose) (29.354 ± 1.607%). Fonio millet extract also showed the best antioxidant activity (significantly higher% inhibition value = 47.909 ± 3.472) and the pearl millet revealed the least antioxidant activity (significantly lower% inhibition value = 44.910 ± 3.597) both at a concentration of 500 mg·ml−1, though all the millet extracts showed activity towards this a...