Comparison of frontostriatal circuits in adolescent nicotine addiction and internet gaming disorder

作者：Karen M. von Deneen, Hadi Hussain, Junaid Waheed, Xinwen Wen, Dahua Yu, Kai Yuan · 发表于：Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) · 年份：2022 · 被引用次数：36 · 研究领域：Impact of Technology on Adolescents、Functional Brain Connectivity Studies、Mental Health Research Topics

Background Recently, there has been significantly increased participation in online gaming and other addictive behaviors particularly in adolescents. Tendencies to avoid social interaction and become more involved in technology-based activities pose the danger of creating unhealthy addictions. Thus, the presence of relatively immature cognitive control and high risk-taking properties makes adolescence a period of major changes leading to an increased rate of emotional disorders and addiction. Aims The critical roles of frontostriatal circuits in addiction have become the primary focus associated with reward in the striatum and cognitive control in the PFC. Internet gaming disorder (IGD) and nicotine addiction are currently becoming more and more serious. Methods In the light of neuroimaging, the similarity between brain mechanisms causing substance use disorder (SUD) and IGD have been described in previous literature. Results In particular, two distinct brain systems affect the way we act accounting for uncharacteristic neural function in addiction: the affective system comprises of the striatum driven by emotional, reward-related, and internal stimuli, and a cognitive system consisting of the prefrontal cortex (PFC) supporting the ventral affective system's actions via inhibitory control. Discussion and Conclusion Therefore, as a novel concept, we focused on the implication of frontostriatal circuits in nicotine addiction and IGD by reviewing the main findings from our studi...