A Facile, Efficient, and General Synthetic Method to Amide-Linked Covalent Organic Frameworks

作者：Zhi‐Bei Zhou, Xianghao Han, Qiao-Yan Qi, Shi‐Xian Gan, De‐Li Ma, Xin Zhao · 发表于：Journal of the American Chemical Society · 年份：2022 · DOI：10.1021/jacs.1c12392 · 被引用次数：244 · 研究领域：Covalent Organic Framework Applications、Metal-Organic Frameworks: Synthesis and Applications、Advanced Photocatalysis Techniques

Amide-linked covalent organic frameworks (amide COFs) possess enormous potentials in practical applications benefiting from their high stability and polyamide structures. However, they suffer from very limited accessibility. Herein, we report a new linkage conversion method to rapidly synthesize crystalline amide COFs through oxidation of imine linkages in their corresponding imine-linked frameworks with KHSO 5 as an oxidant under very mild conditions. This synthetic strategy is general, facile, efficient, and scalable, as demonstrated by the procedure of simply stirring mixtures of imine-linked COFs (seven examples) and KHSO 5 in anhydrous dimethylformamide for several hours to complete the conversions and gram-scale synthesis. The high efficiency of this approach enables facile production of amide COFs from widely available imine-linked COFs, which lays the foundation for exploring practical applications of this unique type of polyamide material.