Hydrogen bond activated glycosylation under mild conditions

作者：Ke Xiao, Yongxin Hu, Yongyong Wan, Xinxin Li, Qin Nie, Hao Yan, Liming Wang, Jin‐Xi Liao, De-Yong Liu, Yuan‐Hong Tu, Jiansong Sun, Jeroen D. C. Codée, Qingju Zhang · 发表于：Chemical Science · 年份：2021 · DOI：10.1039/d1sc05772c · 被引用次数：49 · 研究领域：Carbohydrate Chemistry and Synthesis、Glycosylation and Glycoproteins Research、Chemical Synthesis and Analysis

A mild glycosylation system was developed using glycosyl imidate donors and a charge-enhanced thiourea H-bond donor catalyst. The method can be used for the effective synthesis of O -, C -, S - and N -glycosides and chemoselective one-pot glycosylation.