Heart Failure with Preserved, Mid-Range, and Reduced Ejection Fraction Across Health Care Settings: An Observational Study

作者：Annemarijn R de Boer, Ilonca Vaartjes, Aisha Gohar, Mark J Valk, Jasper J. Brugts, Leandra J M Boonman-de Winter, Evelien ES van Riet, Yvonne van Mourik, Hans‐Peter Brunner‐La Rocca, Gerard C.M. Linssen, Arno W. Hoes, Michiel L. Bots, Hester M. den Ruijter, Frans H. Rutten · 发表于：ESC Heart Failure · 年份：2021 · DOI：10.1002/ehf2.13742 · 被引用次数：28 · 研究领域：Heart Failure Treatment and Management、Cardiovascular Function and Risk Factors、Acute Myocardial Infarction Research

AIMS: This study aimed to assess the sex-specific distribution of heart failure (HF) with preserved, mid-range, and reduced ejection fraction across three health care settings. METHODS AND RESULTS: In this descriptive observational study, we retrieved the distribution of HF types [with reduced ejection fraction (HFrEF), mid-range ejection fraction (HFmrEF), and preserved ejection fraction (HFpEF)] for men and women between 65 and 79 years of age in three health care settings from a single country: (i) patients with screening-detected HF in the high-risk community (i.e. those with shortness of breath, frailty, diabetes mellitus, and chronic obstructive pulmonary disease) from four screening studies, (ii) patients with confirmed HF from primary care derived from a single observational study, and (iii) patients with confirmed HF from outpatient cardiology clinics participating in a registry. Among 1407 patients from the high-risk community, 288 had screen-detected HF (15% HFrEF, 12% HFmrEF, 74% HFpEF), and 51% of the screen-detected HF patients were women. In both women (82%) and men (65%), HFpEF was the most prevalent HF type. In the routine general practice population (30 practices, 70 000 individuals), among the 160 confirmed HF cases, 35% had HFrEF, 23% HFmrEF, and 43% HFpEF, and in total, 43% were women. In women, HFpEF was the most prevalent HF type (52%), while in men, this was HFrEF (41%). In outpatient cardiology clinics (n = 34), of the 4742 HF patients (66% HFrEF, 15%...