Chemical Specification of Gynostemma pentaphyllum (Thunb.) Makino

作者：Warunee Jirawattanapong, Jaree Bansiddhi, Yenchit Techadamrongsin, Duangpen Pattamadilok · 年份：2016 · 研究领域：Hermeneutics and Narrative Identity、Aging, Elder Care, and Social Issues、Health, Medicine and Society

ABSTRACT Gynostemma pentaphyllum (Thunb.) Makino (Cucurbitaceae) is of interest as a potential crude drug. Its chemical constituents were identified as gypenosides, dammarane-type saponins, which possessed various activities: antitumor, antilipemic, and anti-inflammatory activities etc. In this investigation, the quality of G. pentaphyllum collected from 13 various areas, both wild and cultivated, was examined. The chemical identifications were provided by colour reaction, froth test and TLC fingerprint. The efficient methods to determine the total saponins which are pharmaceutically valuable have been developed. Subsequently, the chemical specifications for the aerial parts of this herb were provided. Key words : Gynostemma pentaphyllum, Chemical specification, Total saponins