Chinese Consensus Report on Family-Based Helicobacter pylori Infection Control and Management (2021 Edition)

作者：Songze Ding, Yiqi Du, Hong Lü, Weihong Wang, Hong Cheng, Shi-Yao Chen, Minhu Chen, Weichang Chen, Ye Chen, Jing‐Yuan Fang, Hengjun Gao, Mingzhou Guo, Ying Han, Xiaohua Hou, Fu-lian Hu, Bo Jiang, Hai-Xing Jiang, Chun‐Hui Lan, Jingnan Li, Yan Li, Yan-Qing Li, Jie Liu, Youming Li, Bin Lü, Youyong Lu, Yinglei Miao, Yongzhan Nie, Jiaming Qian, Jianqiu Sheng, Chengwei Tang, Fen Wang, Huahong Wang, Jiangbin Wang, Jingtong Wang, Junping Wang, Xuehong Wang, Kaichun Wu, Xingzhou Xia, Wei‐Fen Xie, Yong Xie, Jian-Ming Xu, Changqing Yang, Guibin Yang, Yuan Yuan, Zhirong Zeng, Bingyong Zhang, Guiying Zhang, Guoxin Zhang, Jianzhong Zhang, Zhenyu Zhang, Pengyuan Zheng, Yin Zhu, Xiuli Zuo, Li-Ya Zhou, Nonghua Lyu, Yunsheng Yang, Zhaoshen Li · 发表于：Gut · 年份：2021 · DOI：10.1136/gutjnl-2021-325630 · 被引用次数：190 · 研究领域：Helicobacter pylori-related gastroenterology studies、Eosinophilic Esophagitis、Microscopic Colitis

Objective Helicobacter pylori infection is mostly a family-based infectious disease. To facilitate its prevention and management, a national consensus meeting was held to review current evidence and propose strategies for population-wide and family-based H. pylori infection control and management to reduce the related disease burden. Methods Fifty-seven experts from 41 major universities and institutions in 20 provinces/regions of mainland China were invited to review evidence and modify statements using Delphi process and grading of recommendations assessment, development and evaluation system. The consensus level was defined as ≥80% for agreement on the proposed statements. Results Experts discussed and modified the original 23 statements on family-based H. pylori infection transmission, control and management, and reached consensus on 16 statements. The final report consists of three parts: (1) H. pylori infection and transmission among family members, (2) prevention and management of H. pylori infection in children and elderly people within households, and (3) strategies for prevention and management of H. pylori infection for family members. In addition to the ‘test-and-treat’ and ‘screen-and-treat’ strategies, this consensus also introduced a novel third ‘family-based H. pylori infection control and management’ strategy to prevent its intrafamilial transmission and development of related diseases. Conclusion H. pylori is transmissible from person to person, and among fa...