Structure of Rift Valley Fever Virus RNA-Dependent RNA Polymerase

作者：Xue Wang, Cuixia Hu, Wei Ye, Jia Wang, Xiaofei Dong, Jie Xu, Xiaorong Li, Manfeng Zhang, Hongyun Lu, Fanglin Zhang, Wei Wu, Shaodong Dai, Hongwei Wang, Zhongzhou Chen · 发表于：Journal of Virology · 年份：2021 · DOI：10.1128/jvi.01713-21 · 被引用次数：39 · 研究领域：Viral Infections and Vectors、Mosquito-borne diseases and control、Vector-Borne Animal Diseases

The zoonosis RVF virus (RVFV) is one of the most serious arbovirus threats to both human and animal health. RNA-dependent RNA polymerase (RdRp) is a multifunctional enzyme catalyzing genome replication as well as viral transcription, so the RdRp is essential for studying the virus and has multiple drug targets.