Research progress in gene editing technology

作者：Sheng Huang, Yali Yan, Fei Su, Xiaorui Huang, Dandan Xia, Xinxin Jiang, Yinghui Dong, Ping Lv, Fangyuan Chen, Yanwei Lv · 发表于：Frontiers in Bioscience-Landmark · 年份：2021 · DOI：10.52586/4997 · 被引用次数：34 · 研究领域：CRISPR and Genetic Engineering、Viral gastroenteritis research and epidemiology、Virus-based gene therapy research

As a tool for modifying the genome, gene editing technology has developed rapidly in recent years, especially in the past two years. With the emergence of new gene editing technologies, such as transposon editing tools, numerous advancements have been made including precise editing of the genome, double base editing, and pilot editing. This report focuses on the development of gene editing tools in recent years, elaborates the progress made in classic editing tools, base editor and other new editing tools, and provides insights into challenges and opportunities.