Functionalized resorcinarenes effectively disrupt the aggregation of αA66-80 crystallin peptide related to cataracts

作者：Kwaku Twum, Avik Bhattacharjee, Erving T. Laryea, Josephine Esposto, George Omolloh, Shaelyn Mortensen, Maya Jaradi, Naomi L. Stock, Nicholas Schileru, Bianca Elias, Elan Pszenica, Theresa M. McCormick, Sanela Martić, Ngong Kodiah Beyeh · 发表于：RSC Medicinal Chemistry · 年份：2021 · DOI：10.1039/d1md00294e · 被引用次数：12 · 研究领域：Connexins and lens biology、Immune Response and Inflammation、S100 Proteins and Annexins

extended aromatic interactions. These results highlight the potential of versatile and tunable functionalized resorcinarenes as potential therapeutics to reverse the aggregation of α-crystallin dominant in eye cataracts.