Controlling the pyridinium–zwitterionic ligand ratio on atomically precise gold nanoclusters allowing for eradicating Gram-positive drug-resistant bacteria and retaining biocompatibility

作者：Zeyang Pang, Qizhen Li, Yuexiao Jia, Weixiao Yan, Jie Qi, Yuan Guo, Fupin Hu, Dejian Zhou, Xingyu Jiang · 发表于：Chemical Science · 年份：2021 · DOI：10.1039/d1sc03056f · 被引用次数：45 · 研究领域：Nanocluster Synthesis and Applications、Advanced Nanomaterials in Catalysis、Pharmacological Effects and Toxicity Studies

and animal models of skin infections. Furthermore, the fluorescence of the gold nanocluster at the second near-infrared (NIR-II) biological window allowed for the monitoring of its biodistribution and body clearance, which confirmed that the gold nanoclusters had good renal clearance and biocompatibility. This study provides a new strategy to combat the MDR challenge using multifunctional gold nanomaterials.