Microbial adaptive evolution

作者：Aiqin Shi, Feiyu Fan, James R. Broach · 发表于：Journal of Industrial Microbiology & Biotechnology · 年份：2021 · DOI：10.1093/jimb/kuab076 · 被引用次数：76 · 研究领域：Genomics and Phylogenetic Studies、Microbial Metabolic Engineering and Bioproduction、Probiotics and Fermented Foods

Bacterial species can adapt to significant changes in their environment by mutation followed by selection, a phenomenon known as "adaptive evolution." With the development of bioinformatics and genetic engineering, research on adaptive evolution has progressed rapidly, as have applications of the process. In this review, we summarize various mechanisms of bacterial adaptive evolution, the technologies used for studying it, and successful applications of the method in research and industry. We particularly highlight the contributions of Dr. L. O. Ingram. Microbial adaptive evolution has significant impact on our society not only from its industrial applications, but also in the evolution, emergence, and control of various pathogens.