The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump

作者：Peng Wu, Wenjing Xiang, Chengke Yin, Li Shu · 发表于：Frontiers in Physiology · 年份：2021 · DOI：10.3389/fphys.2021.766867 · 被引用次数：15 · 研究领域：Mechanical Circulatory Support Devices、Cardiac Structural Anomalies and Repair、Fuel Cells and Related Materials

In recent years, blood pumps have become the bridge to heart transplantation for patients with heart failure. Portability and wearability of blood pumps should be considered to ensure patient satisfaction in everyday life. To date, the focus has been on the development of portable and wearable peripheral components, little attention has been paid to the portable and wearable performance of the blood pump itself. This study reported a novel design of a wearable and portable extracorporeal centrifugal blood pump. Based on an in-house centrifugal maglev blood pump, the wearable and portable blood pump was designed with parallel inlet and outlet pipes to improve the wearable performance. A ring cavity was set at the inlet to convert the circumferential velocity of the inlet pipe to an axial velocity. The hydraulic and hemolytic performance of the baseline and portable blood pumps were analyzed and compared. Compared with the baseline pump, the hydrodynamic and hemolytic performance of the portable pump has been maintained without serious degradation. The results of this study will improve the life quality of patients with heart failure, and enhance the clinical benefits of artificial heart.