Recent advances in transition-metal-catalysed asymmetric coupling reactions with light intervention

作者：Fu‐Dong Lu, Jun Chen, Xuan‐Feng Jiang, Jia‐Rong Chen, Liang‐Qiu Lu, Wen‐Jing Xiao · 发表于：Chemical Society Reviews · 年份：2021 · DOI：10.1039/d1cs00210d · 被引用次数：212 · 研究领域：Radical Photochemical Reactions、Catalytic C–H Functionalization Methods、Sulfur-Based Synthesis Techniques

Transition metal-catalysed asymmetric coupling has been established as a robust tool for constructing complex organic molecules. Although this area has been extensively studied, the development of efficient protocols to construct stereogenic centres with excellent regio- and enantioselectivities is highly desirable and remains challenging. Asymmetric transition metal catalysis with light intervention provides a practical alternative strategy to current methods and considerably expands the synthetic utility as a result of abundant feedstocks and mild conditions. This tutorial review comprehensively summarizes the recent advances in transition-metal-catalysed asymmetric coupling reactions with light intervention; in particular, a concise analysis of substrate scope and the mechanistic scenarios governing stereocontrol is discussed.