Public Willingness and Determinants of COVID-19 Vaccination at the Initial Stage of Mass Vaccination in China

作者：Yimiao Zhao, Lin Liu, Jie Sun, Wei Yan, Kai Yuan, Yongbo Zheng, Zheng-An Lu, Lin Liu, Shuyu Ni, Sizhen Su, Xi-Mei Zhu, Na Zeng, Yi-Miao Gong, Ping Wu, Mao‐Sheng Ran, Yue Leng, Jie Shi, Le Shi, Lin Lü, Yanping Bao · 发表于：Vaccines · 年份：2021 · DOI：10.3390/vaccines9101172 · 被引用次数：43 · 研究领域：Vaccine Coverage and Hesitancy、SARS-CoV-2 and COVID-19 Research、Misinformation and Its Impacts

The present study assessed the willingness of the general population to receive COVID-19 vaccines and identified factors that influence vaccine hesitancy and resistance. A national online survey was conducted from 29 January 2021 to 26 April 2021 in China. Multinomial logistic regression analyses were conducted to identify factors that influence vaccine hesitancy and resistance. Of the 34,041 participants surveyed, 18,810 (55.3%) were willing to get vaccinated, 13,736 (40.3%) were hesitant, and 1495 (4.4%) were resistant. Rates of vaccine acceptance increased over time, with geographical discrepancies in vaccine hesitancy and resistance between provinces in China. Vaccine safety was the greatest concern expressed by most participants (24,461 [71.9%]), and the major reason for participants' refusing vaccination (974 [65.2%]). Government agencies (23,131 [68.0%]) and social media (20,967 [61.6%]) were the main sources of COVID-19 vaccine information. Compared with vaccination acceptance, female, young and middle-aged, high income, and perceived low-risk of infection were associated with vaccine hesitancy. Histories of allergic reactions to other vaccines and depression symptoms were related to vaccine resistance. Common factors that influenced vaccine hesitancy and resistance were residing in cities and perceiving less protection with vaccines than with other protective measures. The results indicate that the rate of vaccine resistance is relatively low, but vaccine hesitancy i...