Persistence of sleep disturbance among post‐COVID patients: Findings from a 2‐month follow‐up study in a Bangladeshi cohort

作者：Md. Khairul Islam, Md. Maruf Ahmed Molla, Pratyay Hasan, Mohiuddin Sharif, Fahima Hossain, Md Robed Amin, Md Ridwanur Rahman · 发表于：Journal of Medical Virology · 年份：2021 · DOI：10.1002/jmv.27397 · 被引用次数：31 · 研究领域：Long-Term Effects of COVID-19、Sleep and related disorders、COVID-19 and Mental Health

Abstract To evaluate the persistence and factors associated with sleep disturbances among COVID‐19 patients with a history of sleep disturbances 2 months after discharge from the hospital. A total of 400 patients admitted at Dhaka Medical College Hospital during July and August were diagnosed as suffering from sleep disturbances during their hospital stay using a standardized scale. They were followed up 2 months later through telephone, and a total of 322 participants were interviewed (excluding 63 nonresponders and five deceased) regarding the persistence of disturbances in sleep through a structured questionnaire. Patient demographic, clinical, and epidemiological data including history regarding in‐hospital sleep disturbance were retrieved from hospital treatment sheets. Results revealed, 35% of study participants (n = 113) were still experiencing symptoms of sleep disturbances during the interview by telephone. Age (p = 0.015), diabetes mellitus (relative risk [RR]: 1.21; confidence interval [CI]: 1.02–1.42, p = 0.022), on admission SPO2 (p = 0.009), C‐reactive protein (CRP) (p = 0.025), serum ferritin (p = 0.014), and d‐dimer (p = 0.030) were independently associated with sleep disturbances among participants (p < 0.05). Binary and fitting logistic regression through repeated K folds cross‐validation revealed 1.65 (CI: 1.02–2.66), 1.07 (CI: 1.01–1.14), and 1.07 (CI: 1.00–1.15) times higher odds of persistence of sleep disturbances among patients with diabetes mellitus, ...