Development of a genetic algorithm and NONMEM workbench for automating and improving population pharmacokinetic/pharmacodynamic model selection

作者：M. Ismail, Mark Sale, Yifan Yu, Nikhil Pillai, Sihang Liu, Beth R. Pflug, Robert R. Bies · 发表于：Journal of Pharmacokinetics and Pharmacodynamics · 年份：2021 · DOI：10.1007/s10928-021-09782-9 · 被引用次数：28 · 研究领域：Statistical Methods in Clinical Trials、Metabolomics and Mass Spectrometry Studies、Pharmacogenetics and Drug Metabolism