Thalidomide: history, withdrawal, renaissance, and safety concerns

作者：Neil Vargesson, Trent D. Stephens · 发表于：Expert Opinion on Drug Safety · 年份：2021 · DOI：10.1080/14740338.2021.1991307 · 被引用次数：51 · 研究领域：Multiple Myeloma Research and Treatments、Protein Degradation and Inhibitors、Computational Drug Discovery Methods

Thalidomide is used around the world today to effectively treat inflammatory and cancer conditions. Yet, 60 years ago, it was withdrawn from the market. What do we know about its mechanisms of acti...