Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

作者：Damian Santomauro, Ana Maria Mantilla Herrera, Jamileh Shadid, Peng Zheng, Charlie Ashbaugh, David M. Pigott, Cristiana Abbafati, Christopher Adolph, Joanne O Amlag, Aleksandr Y. Aravkin, Bree Bang-Jensen, Gregory J Bertolacci, Sabina Bloom, Rachel Castellano, Emma Castro, Suman Chakrabarti, Jhilik Chattopadhyay, Rebecca M Cogen, James K. Collins, Xiaochen Dai, William James Dangel, Carolyn Dapper, Amanda Deen, Megan Erickson, Samuel B Ewald, Abraham D. Flaxman, Joseph Frostad, Nancy Fullman, J Giles, Ababi Zergaw Giref, Gaorui Guo, Jiawei He, Monika Helak, Erin Hulland, Bulat Idrisov, Akiaja Lindstrom, Emily Linebarger, Paulo A. Lotufo, Rafael Lozano, Beatrice Magistro, Déborah Carvalho Malta, Johan Månsson, Fatima Marinho, Ali H. Mokdad, Lorenzo Monasta, Paulami Naik, Shuhei Nomura, James Kevin O'Halloran, Samuel M Ostroff, Maja Pasovic, Louise Penberthy, Robert C. Reiner, Grace Reinke, Antônio Luiz Pinho Ribeiro, Aleksei Sholokhov, Reed J D Sorensen, Elena A. Varavikova, Anh Vo, Rebecca Walcott, Stefanie Watson, Charles Shey Wiysonge, Bethany Zigler, Simon I Hay, Theo Vos, Christopher Murray, Harvey Whiteford, Alize J Ferrari · 发表于：The Lancet · 年份：2021 · DOI：10.1016/s0140-6736(21)02143-7 · 被引用次数：5566 · 研究领域：COVID-19 and Mental Health、COVID-19 and healthcare impacts、Mental Health Research Topics

BACKGROUND: Before 2020, mental disorders were leading causes of the global health-related burden, with depressive and anxiety disorders being leading contributors to this burden. The emergence of the COVID-19 pandemic has created an environment where many determinants of poor mental health are exacerbated. The need for up-to-date information on the mental health impacts of COVID-19 in a way that informs health system responses is imperative. In this study, we aimed to quantify the impact of the COVID-19 pandemic on the prevalence and burden of major depressive disorder and anxiety disorders globally in 2020. METHODS: We conducted a systematic review of data reporting the prevalence of major depressive disorder and anxiety disorders during the COVID-19 pandemic and published between Jan 1, 2020, and Jan 29, 2021. We searched PubMed, Google Scholar, preprint servers, grey literature sources, and consulted experts. Eligible studies reported prevalence of depressive or anxiety disorders that were representative of the general population during the COVID-19 pandemic and had a pre-pandemic baseline. We used the assembled data in a meta-regression to estimate change in the prevalence of major depressive disorder and anxiety disorders between pre-pandemic and mid-pandemic (using periods as defined by each study) via COVID-19 impact indicators (human mobility, daily SARS-CoV-2 infection rate, and daily excess mortality rate). We then used this model to estimate the change from pre-pa...