Enzyme Therapeutic for Ischemia and Reperfusion Injury in Organ Transplantation

作者：Ran Yan, Jie Ren, Jing Wen, Zheng Cao, Di Wu, Meng Qin, Duo Xu, Roxanne Castillo, Feifei Li, Fang Wang, Zhihua Gan, Chaoyong Liu, Ping Wei, Yunfeng Lu · 发表于：Advanced Materials · 年份：2021 · DOI：10.1002/adma.202105670 · 被引用次数：44 · 研究领域：Heme Oxygenase-1 and Carbon Monoxide、Acute Kidney Injury Research、Cardiac Ischemia and Reperfusion

Ischemia-reperfusion injury (IRI) remains as a critical challenge for organ transplantation. Herein, an enzyme therapeutic based on superoxide dismutase and catalase for effective mitigation of IRI and pathogen-induced liver injury is reported, providing a therapeutic for organ transplantation and other diseases.