Rapid quantitation of three synthetic cathinones in urine by magnetic dispersive solid-phase extraction combined with DART-HRMS

作者：Yawen Li, Ru Lian, Feiyu Yang, Zhiru Xu, Fangqi Cao, Rong Wang, Chen Liang, Yurong Zhang · 发表于：Analytical Methods · 年份：2021 · DOI：10.1039/d1ay01280k · 被引用次数：12 · 研究领域：Forensic Toxicology and Drug Analysis、Analytical Chemistry and Chromatography、Mass Spectrometry Techniques and Applications

, respectively. The correlation coefficients were all greater than 0.99. The precision and deviation of accuracy were all within ±15%, and the stability of the samples was high under various conditions. The method was successfully applied to detect 4-Cl-α-PVP, 4-MPD and β-TH-naphyrone in rat urine after subcutaneous administration. In summary, a fast and convenient detection method was established, providing new and effective technical support for the rapid quantitation of three synthetic cathinones (4-Cl-α-PVP, 4-MPD and β-TH-Naphyrone) for forensic purposes.