Adjunctive Probiotics Alleviates Asthmatic Symptoms via Modulating the Gut Microbiome and Serum Metabolome

作者：Ailing Liu, Teng Ma, Ning Xu, Hao Jin, Feiyan Zhao, Lai‐Yu Kwok, Heping Zhang, Shukun Zhang, Zhihong Sun · 发表于：Microbiology Spectrum · 年份：2021 · DOI：10.1128/spectrum.00859-21 · 被引用次数：132 · 研究领域：Gut microbiota and health、Probiotics and Fermented Foods、Asthma and respiratory diseases

The human gut microbiota has a potential effect on the pathogenesis of asthma and is closely related to the disease phenotype. Our trial has demonstrated that co-administering Probio-M8 synergized with conventional therapy to alleviate asthma symptoms. The findings of the present study provide new insights into the pathogenesis and treatment of asthma, mechanisms of novel therapeutic strategies, and application of probiotics-based therapy.