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MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation

作者:Nicolette Driscoll, Brian Erickson, Brendan B. Murphy, Andrew G. Richardson, Tanya Gregory, Nicholas V. Apollo, Georgios Mentzelopoulos, Tyler S. Mathis, Kanit Hantanasirisakul, Puneet Bagga, Sarah E. Gullbrand, Matthew Sergison, Ravinder Reddy, John A. Wolf, H. Isaac Chen, Timothy H. Lucas, Timothy R. Dillingham, Kathryn A. Davis, Yury Gogotsi, John D. Medaglia, Flavia Vitale · 发表于:Science Translational Medicine · 年份:2021 · DOI:10.1126/scitranslmed.abf8629 · 被引用次数:174 · 研究领域:Advanced Memory and Neural Computing、Advanced Sensor and Energy Harvesting Materials、Neuroscience and Neural Engineering

MXene (a two-dimensional transition metal carbide nanomaterial) and scalable solution processing. We show that the electrochemical properties of MXtrodes exceed those of conventional materials and do not require conductive gels when used in epidermal electronics. Furthermore, we validate MXtrodes in applications ranging from mapping large-scale neuromuscular networks in humans to cortical neural recording and microstimulation in swine and rodent models. Last, we demonstrate that MXtrodes are compatible with standard clinical neuroimaging modalities.