Safety and long-term immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Sierra Leone: a combined open-label, non-randomised stage 1, and a randomised, double-blind, controlled stage 2 trial

作者：David Ishola, Daniela Manno, Muhammed O. Afolabi, Babajide Keshinro, Viki Bockstal, Baimba Rogers, Kwabena Owusu-Kyei, Alimamy Serry-Bangura, Ibrahim Swaray, Brett Lowe, Dickens Kowuor, Frank Baiden, Thomas A. Mooney, Elizabeth Smout, Brian Köhn, Godfrey T Otieno, Morrison Jusu, Julie Foster, Mohamed Samai, Gibrilla F. Deen, Heidi J. Larson, Shelley Lees, Neil Goldstein, Katherine E. Gallagher, Auguste Gaddah, Dirk Heerwegh, Benoît Callendret, Kerstin Lühn, Cynthia Robinson, Maarten Leyssen, Brian Greenwood, Macaya Douoguih, Bailah Leigh, Deborah Watson‐Jones, M Kargbo, E Bockarie, N L James, A Kabbah, A Kamara, Kellie Koroma, S O Langley, Naoma William, R Kessebeh, Thomas A. Mooney, Lansana Conteh, Elizabeth Smout, K Allieu, K Bangura, Mohamed Bangura, M A Bangura, H Jalloh, Abdulai Jalloh, I Kamara, M Kamara, Alimamy Saidu Konteh, S Koroma, C Marrah, Mohamed Sesay, Mohamed Sesay, A T Deen, Abdulai Tejan Jalloh, R M Kaimbay, David Kain, A Kamara, E L Kamara, M Kamara, Osman Kamara, I Kamara, Senesie Kamara, M Kanneh, Alusine H. Koroma, D Lahai, I S Mansaray, W S Marah, Massah Massaquoi, A Nabie, N S Saidu, I Samai, J N Tengheh, Abdulai Turay, A Fornah, Fatmata Sesay, A Sow, E Swaray, F Mansaray, T Ade-Cole, Lamin Molecule Bangura, M L Conteh, A Kabbah, Adama Koroma, Mohamed Koroma, Amy Sam, T Scott, T Sessie, J-H C Sunders, Samuel Turay, J Weekes, Mahmud Sheku, Laura Gibson, Dickens Kowuor, Imthiaz Ahamed, W Allieu, D U Kabba, Fatmata Kamara, M S Kebbie, M Pessima, Alie Wurie, Fatoumata Bah, A Bangura, Rohey Bangura, L Blango, S Boima, M Conteh, Y Conteh, M L Daramy, O Fofanah, Elizabeth C. George, Travis Hanson, M I Jalloh, M Kalawa, A M Kamara, F E Kamara, G M Kamara, Halimatu Kamara, P. Kamara, R Kamara, R Kamara, D P Kanneh, M Kanneh, I Komeh, Mohamed Koroma, M Kuyateh, F F Mansaray, M M Mansaray, A B Sillah, M A Tarawally, O S Turya, J B Yawmah, Bailah Leigh, Deborah Watson‐Jones, Brian Greenwood, Mohamed Samai, Gibrilla F. Deen, Dennis Marke, Peter Piot, Peter G. Smith, John Edmunds, Shelley Lees, Heidi J. Larson, Helen A. Weiss, P Wilson, Cathy Maxwell, David Ishola, Muhammed O. Afolabi, Frank Baiden, Pauline Akoo, Kwabena Owusu-Kyei, Daniel Tindanbil, Hilary Bower, J Stuart, Osman Bah, Baimba Rogers, Alimamy Serry-Bangura, Ibrahim Swaray, A Bangura, I J David, Deborah Davies, J A Kallon, A Kamara, Ibrahim Franklyn Kamara, Michael Kamara, Foday Morovia, F Suma, F Thompson, M Murray, F Sesay, Ibrahim Juldeh Sesay, O Kakay, F Suma, Julie Foster, R. Philips, Daniela Manno, K Gallager, Stephanie Cox, Natasha Howard, Mansur Cesay, P Torrani, Suresh D. Sharma, E Snowden, T. Banks, T Harber, Joelle Brown, Kirsten Howard, N Melton, S Malcolm, Sabrina Welsh, Rosalind M. Eggo, Mario Jendrossek, Carl A. B. Pearson, Johan Van Hoof, Macaya Douoguih, K Offergelt, Cynthia Robinson, Babajide Keshinro, M Van Alst, Neal Mahajan, Viki Bockstal, Neil Goldstein, Auguste Gaddah, Dirk Heerwegh, Kerstin Lühn, Maarten Leyssen, Brett Lowe, Ken Awuondo, Hannah Hafezi, Emma Hancox, Brian Köhn, G O Tuda, Fatmata Koroma, A Kamara, G Bangura, Mattu Tehtor Kroma, L Fofanah, A Pessima, M Rogers, O Sheriff, T W Ajala, J Fangawa, S Foday, I Jabbie, B Mansaray, H A Mansaray, K Sesay, M K Charles, P C Heroe, M Lamin Karbo, I S Yansaneh, Seth Gogo Egoeh, A Trye, Monica Amponsah, N D Alghali, Abdulai Jawo Bah, Ibrahim Bangura, Abosede Cole, Kadiatu Fofanah, S Fofanah, H Jalloh, K F N Jalloh, N Jalloh, H U Kabba, Juana Kabba, M Kabba, R Kamara, Jennifer Kamara, F Kanjie, Alpha Kanu, Islam M Kargbo, G Kassa-Koroma, S Koroma, Abdul J. Sankoh, T Sankoh, Osman Sesay, H Wilhem, C Theodore Williams, Ibrahim Bangura, Y Ben-Rogers, Abdulai Tejan Jalloh, F J Jamboria, Nicholas Kamara, I Kanawah, Amanda Kargbo, Ibrahim Swaray, L Amara, Ibrahim Bundu, H B Jakema, Kassim Kamara, Mahmud Sheku, Qadri Adebayo Adeleye, I Akhigbe, R Bakalemwa, Nathalie Chami, Tammy Sylvester, L Altmann, Bomposseh Kamara, Karel Van Roey, P Conteh, Masaru Samura, V Gandie, M Marrah, E Moinina, J Kalokoh, Musa Bangura, Sam Bosompem, Trudi Hilton, Morrison Jusu, P Borboh, Abdulai Salia Brima, A F Y Caulker, A Kallon, Bockarie Koroma, R C Macauley, T M D Saquee, H I Williams, Agnes Bangura, J Fornah, Baimba Idriss, M Sillah, Wilma Mackay, B Aleghen, Tamar Murray, Joseph Edem-Hotah, T Fatorma, F Amara, M Kamara, Sheriff Bangura, E Bonnie, M Sannoh, Ashleigh C. Donaldson, S Ndingi, D Nyaberi, Marcus R. Pereira, Alice Rothwell, V Vy, L Nyallay, Augustin E Fombah, S. N. A. Saidu, Emma Hancox, Nicholas E. Connor, T P Dambo, P J Fakaba, M M E Fatorma, C. L. Johnson, M Kamara, D B Kogba, A Lahai, W S Wong Vincent, N Yambasu, Musa Bangura, Angus Fayia Tengbeh, K Bangura, R Kabia, AM Nyakoi, Michael J. Callaghan, Luisa Enria, S Lee · 发表于：The Lancet Infectious Diseases · 年份：2021 · DOI：10.1016/s1473-3099(21)00125-0 · 被引用次数：96 · 研究领域：Viral Infections and Outbreaks Research、Bacillus and Francisella bacterial research、SARS-CoV-2 and COVID-19 Research