Design, synthesis and biological evaluation of aminopyrimidine derivatives bearing a 4,5,6,7-tetrahydrothieno [3,2-c]pyridine as potent EGFR inhibitors

作者：Yingxue Li, Yaoyao Chang, Jianfang Fu, Rongcai Ding, Lingyun Zhang, Tian Liang, Yajing Liu, Yue Liu, Jinxing Hu · 发表于：European Journal of Medicinal Chemistry · 年份：2021 · DOI：10.1016/j.ejmech.2021.113845 · 被引用次数：21 · 研究领域：Lung Cancer Treatments and Mutations、Quinazolinone synthesis and applications、Cancer therapeutics and mechanisms