Global research publications on irrational use of antimicrobials: call for more research to contain antimicrobial resistance

作者：Waleed M. Sweileh · 发表于：Globalization and Health · 年份：2021 · DOI：10.1186/s12992-021-00754-9 · 被引用次数：72 · 研究领域：Antibiotic Use and Resistance、Pharmaceutical and Antibiotic Environmental Impacts、Antimicrobial agents and applications

BACKGROUND: Irrational use of antimicrobials is highly prevalent. It is a major driving factor for antimicrobial resistance (AMR). Research on irrational antimicrobial use is important for developing policies and regulations to combat and contain AMR. The present study aims to provide an overview of research publications on the irrational use of antimicrobials at the national and global levels. METHODS: Publications on irrational use of antimicrobials were extracted from Scopus using a wide range of relevant keywords for the study period from 1980 to 2020. RESULTS: In total, 656 publications on irrational use of antimicrobials were found. The bulk of publications in this field were about irrational use in humans. A limited number of publications were found on the irrational use of antimicrobials in the context of veterinary and environment. The number of publications, contributing countries, and the mean number of authors per article increased with time, most notably in the last decade. Authors from 105 different countries participated in publishing the retrieved articles with 22 (21.0%) participated in 10 or more publications. The United States led with 140 (21.6%) articles followed distantly by China (n = 49, 7.5%), India (n = 45, 6.9%), and the United Kingdom (n = 45, 6.9%). Countries in the South-East Asian region (n = 69, 10.5%) and the African region (n = 42, 6.4%) made the least contribution. The list of most frequent author keywords included "antimicrobial stewardship...