Current advances in engineering cyanobacteria and their applications for photosynthetic butanol production

作者：Xufeng Liu, Hao Xie, Stamatina Roussou, Peter Lindblad · 发表于：Current Opinion in Biotechnology · 年份：2021 · DOI：10.1016/j.copbio.2021.07.014 · 被引用次数：64 · 研究领域：Photosynthetic Processes and Mechanisms、Algal biology and biofuel production、Microbial Metabolic Engineering and Bioproduction

Cyanobacteria are natural photosynthetic microbes which can be engineered for sustainable conversion of solar energy and carbon dioxide into chemical products. Attempts to improve target production often require an improved understanding of the native cyanobacterial host system. Valuable insights into cyanobacterial metabolism, biochemistry and physiology have been steadily increasing in recent years, stimulating key advancements of cyanobacteria as cell factories for biochemical, including biofuel, production. In the present review, we summarize the current progress in engineering cyanobacteria and discuss the achieved and potential utilization of these advances in cyanobacteria for the production of the bulk chemical butanol, specifically isobutanol and 1-butanol.