TroR Negatively Regulates the TroABCD System and Is Required for Resistance to Metal Toxicity and Virulence in Streptococcus suis

作者：Chengkun Zheng, Man Wei, Jun Qiu, Mengdie Jia, Xiaohui Zhou, Xinan Jiao · 发表于：Applied and Environmental Microbiology · 年份：2021 · DOI：10.1128/aem.01375-21 · 被引用次数：33 · 研究领域：Streptococcal Infections and Treatments、Neonatal and Maternal Infections、Antimicrobial Resistance in Staphylococcus

operon, which has been demonstrated to be involved in manganese acquisition in S. suis. Moreover, we demonstrated that TroR is required for the virulence of S. suis in an intranasal mouse model. Collectively, these results suggest that TroR is a negative regulator of the TroABCD system and contributes to resistance to metal toxicity and virulence in S. suis.