Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption

作者：Michelle M. McDonald, Weng Hua Khoo, Pei Ying Ng, Ya Xiao, Jad Zamerli, Peter Thatcher, Wunna Kyaw, Karrnan Pathmanandavel, Abigail K. Grootveld, Imogen Moran, Danyal Butt, Akira Nguyen, Alexander P. Corr, Sean Warren, Maté Biro, Natalie C. Butterfield, Siobhan E. Guilfoyle, Davide Komla‐Ebri, Michael R.G. Dack, Hannah F. Dewhurst, John G. Logan, Yongxiao Li, Sindhu T. Mohanty, Niall Byrne, Rachael Terry, Marija K. Simic, Ryan C. Chai, Julian M.W. Quinn, Scott E. Youlten, Jessica A. Pettitt, David Abi‐Hanna, Rohit Jain, Wolfgang Weninger, Mischa Lundberg, Shuting Sun, Frank H. Ebetino, Paul Timpson, Woei Ming Lee, Paul A. Baldock, Michael J. Rogers, Robert Brink, Graham R. Williams, J. H. Duncan Bassett, John P. Kemp, Nathan J. Pavlos, Peter I. Croucher, Tri Giang Phan · 发表于：Cell · 年份：2021 · DOI：10.1016/j.cell.2021.03.010 · 被引用次数：100 · 研究领域：Bone Metabolism and Diseases、Bone health and treatments、Biomarkers in Disease Mechanisms

(Cell 184, 1330–1347.e1–e13; March 4, 2021) As a result of an author oversight in the originally published version of this article, the name of an author, Alexander Corr, did not appear in the author list. This error has now been corrected in the article online, and the author contributions have been updated accordingly to reflect Alexander Corr’s contributions to the scRNA-seq analysis. Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorptionMcDonald et al.CellFebruary 25, 2021In BriefTracking osteoclasts during cycles of fission and fusion reveals a transcriptionally distinct “osteomorph” population that are fusion competent, motile, and capable of forming osteoclasts that resorb bone. Full-Text PDF Open Access