An intelligent T 1 – T 2 switchable MRI contrast agent for the non-invasive identification of vulnerable atherosclerotic plaques

作者：Chunshu Pan, Junjie Lin, Jianjun Zheng, Chuang LIU, Bo Yuan, Ozioma Udochukwu Akakuru, M. Zubair Iqbal, Qianlan Fang, Jiapeng Hu, Jia Chen, Jie Lin, Qi Dai, Xiuyu Guo, Zihou Li, Tao Zhang, Xu Chen, Xuehua Ma, Tianxiang Chen, Aiguo Wu, Yinhua Jin · 发表于：Nanoscale · 年份：2021 · DOI：10.1039/d0nr08039j · 被引用次数：38 · 研究领域：Proteoglycans and glycosaminoglycans research、Protease and Inhibitor Mechanisms、Characterization and Applications of Magnetic Nanoparticles

A T 1 – T 2 switchable MRI contrast agent, hyaluronic acid-modified iron oxide nanoparticle–polyacrylic acid, is used for the identification of vulnerable atherosclerotic plaques by macrophage phagocytosis. It could reveal promising enhancement in MRI.