Silver-Mediated [2 + 2 + 1] Cyclization Reaction of Diynes with Elemental Selenium/Sulfur To Synthesize 3,4-Substituted Cyclopenta[ c ]selenophenes/Cyclopenta[ c ]thiophenes

作者：Ye Wang, Yang Yuan, Zongkang Wang, Yingge Gu, Siyi Fu, Lingkai Kong, Yanzhong Li · 发表于：Organic Letters · 年份：2021 · DOI：10.1021/acs.orglett.1c02018 · 被引用次数：21 · 研究领域：Sulfur-Based Synthesis Techniques、Organoselenium and organotellurium chemistry、Catalytic C–H Functionalization Methods

An efficient and atom-economical silver-mediated [2 + 2 + 1] cyclization protocol for the synthesis of 3,4-fused-ring-substituted and 2,5-unsubstituted selenophenes or thiophenes has been developed. Two C-Se/C-S bonds and one C-C bond were rapidly constructed in one step. Readily accessible substrates, commercially available elemental selenium/sulfur, and good functional group tolerance make this procedure attractive for the synthesis of π-conjugated material molecules.