One pot synthesis of aryl nitriles from aromatic aldehydes in a water environment

作者：Hongyan Lin, Ziling Zhou, Xiaopeng Ma, Qingqing Chen, Hongwei Han, Xiaoming Wang, Jinliang Qi, Yonghua Yang · 发表于：RSC Advances · 年份：2021 · DOI：10.1039/d1ra03559b · 被引用次数：9 · 研究领域：Chemical Synthesis and Reactions、Multicomponent Synthesis of Heterocycles、Asymmetric Hydrogenation and Catalysis

In this study, we found a green method to obtain aryl nitriles from aromatic aldehyde in water. This simple process was modified from a conventional method. Compared with those approaches, we used water as the solvent instead of harmful chemical reagents. In this one-pot conversion, we got twenty-five aryl nitriles conveniently with pollution to the environment being minimized. Furthermore, we confirmed the reaction mechanism by capturing the intermediates, aldoximes.