Drug Repurposing: An Alternative Strategy to Treat COVID-19

作者：Pengyu Han, Huifang Zheng, P. Y. Wen, Pan Li, Dan Geng, Dianxing Sun · 发表于：Current Pharmaceutical Biotechnology · 年份：2021 · DOI：10.2174/1389201022666210709141320 · 研究领域：Computational Drug Discovery Methods、SARS-CoV-2 and COVID-19 Research、COVID-19 Clinical Research Studies

In order to curve the ongoing trend of the COVID-19 pandemic and save more lives, effective treatments against COVID-19 are urgently needed. Compared to developing new drugs, which may take too much time, it's more efficient and cost-effective to repurpose existing drugs in the treatment of COVID-19. Fortunately, some of the shared features of COVID-19 and other wellknown diseases make it possible to use old strategies to combat this new challenge. In this paper, we reviewed various possible strategies of drug repurposing in the treatment of COVID-19 and explored the possible scientific mechanisms behind each strategy.