Antiviral Effects of Green Tea EGCG and Its Potential Application against COVID-19

作者：Yingqi Wang, Qingsheng Li, Xin‐Qiang Zheng, Jian‐Liang Lu, Yue‐Rong Liang · 发表于：Molecules · 年份：2021 · DOI：10.3390/molecules26133962 · 被引用次数：78 · 研究领域：Tea Polyphenols and Effects、Tryptophan and brain disorders、Atherosclerosis and Cardiovascular Diseases

(–)-Epigallocatechin-3-O-gallate (EGCG), the most abundant component of catechins in tea (Camellia sinensis (L.) O. Kuntze), plays a role against viruses through inhibiting virus invasiveness, restraining gene expression and replication. In this paper, the antiviral effects of EGCG on various viruses, including DNA virus, RNA virus, coronavirus, enterovirus and arbovirus, were reviewed. Meanwhile, the antiviral effects of the EGCG epi-isomer counterpart (+)-gallocatechin-3-O-gallate (GCG) were also discussed.