Impact of Public Health Policies on Alcohol‐Associated Liver Disease in Latin America: An Ecological Multinational Study

作者：Luis Antonio Díaz, Francisco Idalsoaga, Eduardo Fuentes–López, Andrea Márquez‐Lomas, Carolina Ramírez, Juan Pablo Roblero, Roberta Chaves Araújo, Fátima Higuera‐de‐la‐Tijera, Luis Toro, Galo Pazmiño, Pedro Montes, Nelia Hernández, Manuel Mendizábal, Óscar Corsi, Catterina Ferreccio, Mariana Lazo, Mayur Brahmania, Ashwani K. Singal, Ramón Bataller, Marco Arrese, Juan Pablo Arab · 发表于：Hepatology · 年份：2021 · DOI：10.1002/hep.32016 · 被引用次数：74 · 研究领域：Alcohol Consumption and Health Effects、Substance Abuse Treatment and Outcomes、Alcoholism and Thiamine Deficiency

BACKGROUND AND AIMS: Alcohol-associated liver disease (ALD) is the leading cause of liver-related mortality in Latin America, yet the impact of public health policies (PHP) on liver disease is unknown. We aimed to assess the association between alcohol PHP and deaths due to ALD in Latin American countries. APPROACH AND RESULTS: We performed an ecological multinational study including 20 countries in Latin America (628,466,088 inhabitants). We obtained country-level sociodemographic information from the World Bank Open Data source. Alcohol-related PHP data for countries were obtained from the World Health Organization Global Information System of Alcohol and Health. We constructed generalized linear models to assess the association between the number of PHP (in 2010) and health outcomes (in 2016). In Latin America, the prevalence of obesity was 27% and 26.1% among male and female populations, respectively. The estimated alcohol per capita consumption among the population at 15 years old or older was 6.8 L of pure alcohol (5.6 recorded and 1.2 unrecorded). The overall prevalence of alcohol use disorders (AUD) was 4.9%. ALD was the main cause of cirrhosis in 64.7% of male and 40.0% of female populations. A total of 19 (95%) countries have at least one alcohol-related PHP on alcohol. The most frequent PHP were limiting drinking age (95%), tax regulations (90%), drunk-driving policies and countermeasures (90%), and government monitoring systems and community support (90%). A highe...