Efficacy of rikkosan for primary burning mouth syndrome: a retrospective study

作者：Hiroyuki Hato, Ken‐ichiro Sakata, Jun Sato, Takuya Asaka, Noritaka Ohga, Yutaka Yamazaki, Yoshimasa Kitagawa · 发表于：BioPsychoSocial Medicine · 年份：2021 · DOI：10.1186/s13030-021-00221-2 · 被引用次数：8 · 研究领域：Salivary Gland Disorders and Functions、Traditional Chinese Medicine Studies、Pharmacological Effects of Natural Compounds

BACKGROUND: Burning mouth syndrome (BMS) is a chronic condition characterized by pain in the oral cavity. Kampo medicine is a traditional Japanese medical system that has its roots partly in ancient Chinese medicine. The purpose of this study is to evaluate the efficacy of rikkosan-a traditional Japanese herbal medicine (Kampo)-in the treatment of primary BMS. MAIN BODY: A single-center retrospective study was conducted in 32 patients who were diagnosed with primary BMS and treated with rikkosan alone through gargling (2.5 g rikkosan dissolved in 50 mL hot water) three times daily. Patients were asked to evaluate their pain using a numerical rating scale (NRS) at first visit and after 1 month. One patient had stomatitis as a side effect after gargling with rikkosan, however, no side effects were observed in other patients. Overall NRS scores decreased significantly between the first visit (7.6 ± 2.7) and the 1-month visit (5.6 ± 2.8). CONCLUSIONS: Rikkosan may be an effective treatment for primary BMS.