Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies

作者：Wayne Vuong, Conrad Fischer, Muhammad Bashir Khan, Marco J. van Belkum, Tess Lamer, Kurtis D. Willoughby, Jimmy Lu, Elena Arutyunova, Michael Joyce, Holly A. Saffran, Justin Shields, Howard S. Young, James A. Nieman, D. Lorne Tyrrell, M. Joanne Lemieux, John C. Vederas · 发表于：European Journal of Medicinal Chemistry · 年份：2021 · DOI：10.1016/j.ejmech.2021.113584 · 被引用次数：97 · 研究领域：Computational Drug Discovery Methods、Pharmacological Effects of Natural Compounds、SARS-CoV-2 and COVID-19 Research