A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit

作者：Andreas Schedlbauer, Idoia Iturrioz, Borja Ochoa-Lizarralde, Tammo Diercks, Jorge P. López‐Alonso, José Luis Lavín, Tatsuya Kaminishi, Retina Çapuni, Neha Dhimole, Elisa de Astigarraga, David Gil‐Carton, Paola Fucini, Sean R. Connell · 发表于：Science Advances · 年份：2021 · DOI：10.1126/sciadv.abf7547 · 被引用次数：50 · 研究领域：RNA and protein synthesis mechanisms、RNA modifications and cancer、Genomics and Chromatin Dynamics

ribosomal RNA central to decoding site maturation and suggests both a sequential order of action and molecular mechanisms for the assembly factors in coordinating and controlling this switch. Structural and mechanistic parallels between bacterial and eukaryotic systems indicate common folding features inherent to all ribosomes.