Changes in the incidence of invasive disease due to Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis during the COVID-19 pandemic in 26 countries and territories in the Invasive Respiratory Infection Surveillance Initiative: a prospective analysis of surveillance data

作者：Angela B. Brueggemann, Melissa J. Jansen van Rensburg, David R. Shaw, Noel Denis McCarthy, Keith A. Jolley, Martin C. J. Maiden, Mark van der Linden, Zahin Amin‐Chowdhury, Désirée E. Bennett, Ray Borrow, Maria-Cristina C Brandileone, Karen Broughton, Ruth Campbell, Bin Cao, Carlo Casanova, Eun Hwa Choi, Yiu Wai Chu, S. A. Clark, Heike Claus, Juliana Coelho, Mary Corcoran, Simon L. Cottrell, Robert Cunney, Tine Dalby, Heather Davies, Linda de Gouveia, Ala‐Eddine Deghmane, Walter Demczuk, Stefanie Desmet, Richard John Drew, Mignon du Plessis, Helga Erlendsdóttir, Norman K. Fry, Kurt Fuursted, Steve J Gray, Birgitta Henriques‐Normark, Thomas N. Hale, Markus Hilty, Steen Hoffmann, H. Humphreys, Margaret Ip, Susanne Jacobsson, Jillian Johnston, Jana Kozáková, Karl Gustaf Kristinsson, Pavla Křížová, Alicja Kuch, Shamez N Ladhani, Thiên‐Trí Lâm, Vera Lebedova, Laura Lindholm, David J. Litt, Irene Etayo Martín, Delphine Martiny, Wesley Mattheus, Martha McElligott, Mary Meehan, Susan T. Meiring, Paula Mölling, Eva Morfeldt, Julie E. Morgan, Robert Mulhall, Carmen Muñoz‐Almagro, David R. Murdoch, Joy Murphy, Martin Musílek, A. Mzabi, Amaresh Pérez-Argüello, Monique Perrin, Malorie Perry, Alba Redin, Richard J. Roberts, Maria Roberts, Assaf Rokney, M. Ron, Kevin J Scott, Carmen L. Sheppard, Lotta Siira, Anna Skoczyńska, Monica Sloan, Hans‐Christian Slotved, Andrew J. Smith, Joon Young Song, Muhamed-Kheir Taha, Maija Toropainen, Dominic N.C. Tsang, Anni Vainio, Nina M. van Sorge, Emmanuelle Varon, J. Vlach, Ulrich Felix Vogel, Sandra Vohrnova, Anne von Gottberg, Rosemeire Cobo Zanella, Fei Zhou · 发表于：The Lancet Digital Health · 年份：2021 · DOI：10.1016/s2589-7500(21)00077-7 · 被引用次数：555 · 研究领域：Bacterial Infections and Vaccines、Pneumonia and Respiratory Infections、Virology and Viral Diseases

BACKGROUND: Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis, which are typically transmitted via respiratory droplets, are leading causes of invasive diseases, including bacteraemic pneumonia and meningitis, and of secondary infections subsequent to post-viral respiratory disease. The aim of this study was to investigate the incidence of invasive disease due to these pathogens during the early months of the COVID-19 pandemic. METHODS: In this prospective analysis of surveillance data, laboratories in 26 countries and territories across six continents submitted data on cases of invasive disease due to S pneumoniae, H influenzae, and N meningitidis from Jan 1, 2018, to May, 31, 2020, as part of the Invasive Respiratory Infection Surveillance (IRIS) Initiative. Numbers of weekly cases in 2020 were compared with corresponding data for 2018 and 2019. Data for invasive disease due to Streptococcus agalactiae, a non-respiratory pathogen, were collected from nine laboratories for comparison. The stringency of COVID-19 containment measures was quantified using the Oxford COVID-19 Government Response Tracker. Changes in population movements were assessed using Google COVID-19 Community Mobility Reports. Interrupted time-series modelling quantified changes in the incidence of invasive disease due to S pneumoniae, H influenzae, and N meningitidis in 2020 relative to when containment measures were imposed. FINDINGS: 27 laboratories from 26 countries and territ...