PIEZO ion channel is required for root mechanotransduction in Arabidopsis thaliana

作者：Seyed Ali Reza Mousavi, Adrienne E. Dubin, Wei-Zheng Zeng, Adam M. Coombs, Khai Do, Darian A. Ghadiri, William Thomas Keenan, Chennan Ge, Yunde Zhao, Ardem Patapoutian · 发表于：Proceedings of the National Academy of Sciences · 年份：2021 · DOI：10.1073/pnas.2102188118 · 被引用次数：126 · 研究领域：Erythrocyte Function and Pathophysiology、Cellular Mechanics and Interactions、Chemical and Physical Studies

Significance Underground barriers caused by drought or heterogeneous soil components exert mechanical resistance to plants, and plant roots must determine whether to avoid or penetrate these barriers. Yet, very little is known about how roots sense mechanical forces at the molecular level. Using genetics, electrophysiology, and in vivo imaging, we found that Arabidopsis PIEZO1, an ortholog of mammalian Piezo, is required for root penetration and that pzo1 mutants have impaired primary root growth into harder media. These results highlight a conserved function of PIEZOs from plants to mammals.