Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives

作者：Magdalena Bohutínská, Jakub Vlček, Sivan Yair, Benjamin Laenen, Veronika Konečná, Marco Fracassetti, Tanja Slotte, Filip Kolář · 发表于：Proceedings of the National Academy of Sciences · 年份：2021 · DOI：10.1073/pnas.2022713118 · 被引用次数：157 · 研究领域：Genetic diversity and population structure、Genomics and Phylogenetic Studies、Genetic Mapping and Diversity in Plants and Animals

Significance Repeated evolution tends to be more predictable. The impressive spectrum of recent reports on genomic parallelism, however, revealed that the fraction of the genome that evolves in parallel varies greatly, possibly reflecting different evolutionary scales investigated. Here, we demonstrate divergence-dependent parallelism using a comprehensive genome-wide dataset comprising 12 cases of parallel alpine adaptation and identify decreasing probability of adaptive re-use of genetic variation as the major underlying cause. This finding empirically demonstrates that evolutionary predictability is scale dependent and suggests that availability of preexisting variation drives parallelism within and among populations and species. Altogether, our results inform the ongoing discussion about the (un)predictability of evolution, relevant for applications in pest control, nature conservation, or the evolution of pathogen resistance.